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doxycycline Correlation and Cox proportional hazard survival analysis of microarray data from 295 consecutive early breast cancer patients from the Netherlands Cancer Institute identified 240 patient tumors with a gene expression profile E cadherin profile 4 that positively correlated with the E cadherin signature 2, and showed E cadherin signature 2 as predictive of metastasis with a univariate hazard ratio for metastasis of 0
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